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The axonal repellent, Slit2, inhibits directional migration of circulating neutrophils
Author(s) -
Tole Soumitra,
Mukovozov Ilya M.,
Huang YiWei,
Magalhaes Marco A. O.,
Yan Ming,
Crow Min Rui,
Liu Guang Ying,
Sun Chun Xiang,
Durocher Yves,
Glogauer Michael,
Robinson Lisa A.
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0609391
Subject(s) - chemotaxis , microbiology and biotechnology , cell migration , biology , inflammation , n formylmethionine leucyl phenylalanine , receptor , immunology , signal transduction , cell , biochemistry
Slit2, a potentially powerful anti‐inflammatory agent, inhibits polarization and chemotaxis, but not random movement, of primary neutrophils towards diverse chemoattractants, in vitro and in vivo.