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Pivotal Advance: Phospholipids determine net membrane surface charge resulting in differential localization of active Rac1 and Rac2
Author(s) -
Magalhaes Marco A. O.,
Glogauer Michael
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0609390
Subject(s) - biology , rac1 , differential (mechanical device) , microbiology and biotechnology , membrane , biophysics , net (polyhedron) , biochemistry , physics , signal transduction , mathematics , geometry , thermodynamics
Neutrophils regulate membrane lipid composition and membrane surface charge to localize signaling pathways through the recruitment of differentially charged proteins.

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