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Adenosine A 2A receptor activation limits graft‐versus‐host disease after allogenic hematopoietic stem cell transplantation
Author(s) -
Lappas Courtney M.,
Liu PoChing,
Linden Joel,
Kang Elizabeth M.,
Malech Harry L.
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0609388
Subject(s) - hematopoietic stem cell transplantation , immunology , il 2 receptor , proinflammatory cytokine , cd8 , agonist , graft versus host disease , chemokine , haematopoiesis , transplantation , stem cell , t cell , biology , medicine , inflammation , receptor , immune system , genetics
The selective activation of the A 2A has therapeutic potential in both the prevention and treatment of acute GVHD.
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