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IL‐15 protects antigen‐specific CD8 + T cell contraction after Mycobacterium bovis bacillus Calmette‐Guérin infection
Author(s) -
Tang Ce,
Yamada Hisakata,
Shibata Kensuke,
Yoshida Shinichi,
Wajjwalku Worawidh,
Yoshikai Yasunobu
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0608363
Subject(s) - biology , mycobacterium bovis , antigen , microbiology and biotechnology , cd8 , immunology , mycobacterium tuberculosis , pathology , tuberculosis , medicine
In vivo administration of IL‐15 at the contraction phase in BCG infection inhibited apoptosis of effector CD8 + T cells resulting in the significant increase of Ag‐specific memory CD8 + T cells.