Premium
Rac1 and Rac2 control distinct events during antigen‐stimulated mast cell exocytosis
Author(s) -
Baier Alicia,
Ndoh Vivian N. E.,
Lacy Paige,
Eitzen Gary
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0513281
Subject(s) - exocytosis , membrane ruffling , microbiology and biotechnology , biology , rac1 , calcium in biology , mast cell , calcium signaling , rac gtp binding proteins , calcium , intracellular , signal transduction , secretion , cell , biochemistry , immunology , chemistry , cytoskeleton , organic chemistry
Regulation of mast cell granule exocytosis utilizes Rac1 to control actin‐mediated morphological transitions, and Rac2 to control calcium influx.