Premium
Investigation of the differential potentials of TLR agonists to elicit uveitis in mice
Author(s) -
Allensworth Jordan J.,
Planck Stephen R.,
Rosenbaum James T.,
Rosenzweig Holly L.
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0511249
Subject(s) - tlr5 , tlr2 , immunology , biology , uveitis , tlr4 , cytokine , tlr7 , tlr3 , chemokine , tlr9 , inflammation , interleukin 10 , innate immune system , in vivo , cxcl10 , toll like receptor , immune system , biochemistry , gene expression , dna methylation , microbiology and biotechnology , gene
Agonists for seven TLRs induce similar responses when tested in murine iris/ciliary body cultures and have more disparate responses when tested in eyes in vivo.