The glucocorticoid dexamethasone programs human dendritic cells for enhanced phagocytosis of apoptotic neutrophils and inflammatory response | Zendy

Hodrea Judit | Zendy; Majai Gyöngyike | Zendy; Doró Zoltán | Zendy; Zahuczky Gábor | Zendy; Pap Attila | Zendy; Rajnavölgyi Éva | Zendy; Fésüs László | Zendy

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The glucocorticoid dexamethasone programs human dendritic cells for enhanced phagocytosis of apoptotic neutrophils and inflammatory response

Author(s) -

Hodrea Judit,

Majai Gyöngyike,

Doró Zoltán,

Zahuczky Gábor,

Pap Attila,

Rajnavölgyi Éva,

Fésüs László

Publication year - 2012

Publication title -

journal of leukocyte biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.819

H-Index - 191

eISSN - 1938-3673

pISSN - 0741-5400

DOI - 10.1189/jlb.0511243

Subject(s) - proinflammatory cytokine , cd14 , mertk , biology , phagocytosis , microbiology and biotechnology , immunology , apoptosis , dendritic cell , priming (agriculture) , inflammation , immune system , signal transduction , biochemistry , botany , germination , receptor tyrosine kinase

Differentiation of DC with dexamethasone leads to elevated apoptotic neutrophil phagocytosis, through the up‐regulation of apoptophagocytic genes, and to proinflammatory T cell response.

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