TLR2‐dependent modulation of dendritic cells by LT‐IIa‐B 5 , a novel mucosal adjuvant derived from a type II heat‐labile enterotoxin | Zendy

Lee Chang Hoon | Zendy; MassoWelch Patricia | Zendy; Hajishengallis George | Zendy; Connell Terry D. | Zendy

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TLR2‐dependent modulation of dendritic cells by LT‐IIa‐B 5 , a novel mucosal adjuvant derived from a type II heat‐labile enterotoxin

Author(s) -

Lee Chang Hoon,

MassoWelch Patricia,

Hajishengallis George,

Connell Terry D.

Publication year - 2011

Publication title -

journal of leukocyte biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.819

H-Index - 191

eISSN - 1938-3673

pISSN - 0741-5400

DOI - 10.1189/jlb.0511236

Subject(s) - biology , cd80 , adjuvant , cd86 , tlr2 , immune system , immunology , enterotoxin , c c chemokine receptor type 7 , dendritic cell , in vivo , cd40 , t cell , in vitro , chemokine , innate immune system , gene , biochemistry , cytotoxic t cell , escherichia coli , chemokine receptor , microbiology and biotechnology

The immunomodulatory activities of LT‐IIa‐B5 depend upon the adjuvantsˈs capacity to activate and promote migration of DC in mucosal tissues in a strictly TLR2‐dependent manner.

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