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Differentiation of CD8 + T cells into effector cells is enhanced by physiological range hyperthermia
Author(s) -
Mace Thomas A.,
Zhong Lingwen,
Kilpatrick Casey,
Zynda Evan,
Lee ChenTing,
Capitano Maegan,
Minderman Hans,
Repasky Elizabeth A.
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0511229
Subject(s) - biology , cytotoxic t cell , cd8 , splenocyte , antigen , effector , microbiology and biotechnology , cd28 , immunology , biochemistry , in vitro
Fever‐range elevation of body temperature enhances antigenspecific naïe CD8 + T cell differentiation into effector cells and results in clustering of cholesterol dependent‐microdomains in the plasma membrane.