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Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection
Author(s) -
Karmaus Peer W. F.,
Chen Weimin,
Crawford Robert B.,
Harkema Jack R.,
Kaplan Barbara L. F.,
Kaminski Norbert E.
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0511219
Subject(s) - biology , inflammation , immunity , immunology , function (biology) , receptor , cannabinoid , immune system , microbiology and biotechnology , genetics
Deletion of cannabinoid receptors 1 and 2 causes increased sensitivity to immune activation in APC, thereby exacerbating inflammation and cellular immune responses to influenza infection.