Loss of TRPC1‐mediated Ca 2+  influx contributes to impaired degranulation in Fyn‐deficient mouse bone marrow‐derived mast cells | Zendy

Suzuki Ryo | Zendy; Liu Xibao | Zendy; Olivera Ana | Zendy; Aguiniga Lizath | Zendy; Yamashita Yumi | Zendy; Blank Ulrich | Zendy; Ambudkar Indu | Zendy; Rivera Juan | Zendy

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Loss of TRPC1‐mediated Ca 2+ influx contributes to impaired degranulation in Fyn‐deficient mouse bone marrow‐derived mast cells

Author(s) -

Suzuki Ryo,

Liu Xibao,

Olivera Ana,

Aguiniga Lizath,

Yamashita Yumi,

Blank Ulrich,

Ambudkar Indu,

Rivera Juan

Publication year - 2010

Publication title -

journal of leukocyte biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.819

H-Index - 191

eISSN - 1938-3673

pISSN - 0741-5400

DOI - 10.1189/jlb.0510253

Subject(s) - orai1 , fyn , degranulation , microbiology and biotechnology , biology , stim1 , calcium in biology , thapsigargin , voltage dependent calcium channel , calcium , intracellular , medicine , phosphorylation , biochemistry , proto oncogene tyrosine protein kinase src , receptor , endoplasmic reticulum

Fyn‐dependent expression of the cationic transient receptor potential channel 1 contributes to mast cell Ca 2+ influx, cortical F‐actin depolymerization, and degranulation.

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