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Comparison of sensitivity of Th1, Th2, and Th17 cells to Fas‐mediated apoptosis
Author(s) -
Fang Yujiang,
Yu Shiguang,
Ellis Jason S.,
Sharav Tumenjargal,
BraleyMullen Helen
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0509352
Subject(s) - apoptosis , flip , biology , fas ligand , immune system , microbiology and biotechnology , fas receptor , t cell , immunology , cancer research , programmed cell death , biochemistry
Decreased FasL and increased FLIP expression levels in Th17 cells correlated with their decreased sensitivity to Fas‐mediated apoptosis as compared to Th1 cells.