Higher activation of TLR9 in plasmacytoid dendritic cells by microbial DNA compared with self‐DNA based on CpG‐specific recognition of phosphodiester DNA | Zendy

Coch Christoph | Zendy; Busch Nicolas | Zendy; Wimmenauer Vera | Zendy; Hartmann Evelyn | Zendy; Janke Markus | Zendy; AbdelMottaleb Mona Mohamed Ahmed | Zendy; Lamprecht Alf | Zendy; Ludwig Janos | Zendy; Barchet Winfried | Zendy; Schlee Martin | Zendy; Hartmann Gunther | Zendy

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Higher activation of TLR9 in plasmacytoid dendritic cells by microbial DNA compared with self‐DNA based on CpG‐specific recognition of phosphodiester DNA

Author(s) -

Coch Christoph,

Busch Nicolas,

Wimmenauer Vera,

Hartmann Evelyn,

Janke Markus,

AbdelMottaleb Mona Mohamed Ahmed,

Lamprecht Alf,

Ludwig Janos,

Barchet Winfried,

Schlee Martin,

Hartmann Gunther

Publication year - 2009

Publication title -

journal of leukocyte biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.819

H-Index - 191

eISSN - 1938-3673

pISSN - 0741-5400

DOI - 10.1189/jlb.0509314

Subject(s) - phosphodiester bond , dna , biology , cpg site , dna methylation , microbiology and biotechnology , biochemistry , recombinant dna , cpg oligodeoxynucleotide , gene , rna , gene expression

Mammalian genomic DNA complexed to the natural antimicrobial cationic peptide LL37 induces type I interferon but less than bacterial DNA or CG‐dinucleotide containing oligodeoxynucleotides.

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