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Recycling endosome‐dependent and ‐independent mechanisms for IL‐10 secretion in LPS‐activated macrophages
Author(s) -
Stanley A. C.,
Lieu Z. Z.,
Wall A. A.,
Venturato J.,
Khromykh T.,
Hamilton N. A.,
Gleeson P. A.,
Stow J. L.
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0412191
Subject(s) - endosome , secretion , microbiology and biotechnology , proinflammatory cytokine , biology , golgi apparatus , inflammasome , cytokine , intracellular , macrophage , tlr4 , inflammation , signal transduction , immunology , biochemistry , endoplasmic reticulum , in vitro
Two post‐Golgi pathways where IL‐10 is trafficked, ensures its secretion from activated macrophages under different physiological conditions.