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Pivotal Advance: Invariant NKT cells reduce accumulation of inflammatory monocytes in the lungs and decrease immune‐pathology during severe influenza A virus infection
Author(s) -
Kok Wai Ling,
Denney Laura,
Benam Kambez,
Cole Suzanne,
Clelland Colin,
McMichael Andrew J.,
Ho LingPei
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0411184
Subject(s) - immune system , biology , immunology , inflammation , innate immune system , influenza a virus , virus , lung , medicine
iNKT cells modulate severe influenza by reducing accumulation of inflammatory monocytes in lungs; possibly by targeting infected inflammatory monocytes for lysis.