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TLR‐mediated B cell activation results in ectopic CLIP expression that promotes B cell‐dependent inflammation
Author(s) -
Newell M. K.,
Tobin R. P.,
Cabrera J. H.,
Sorensen M. B.,
Huckstep A.,
VillalobosMenuey E. M.,
Burnett M.,
McCrea E.,
Harvey C. P.,
Buddiga A.,
BarOr A.,
Freedman M. S.,
Nalbantoglu J.,
Arbour N.,
Zamvil S. S.,
Antel J. P.
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0410237
Subject(s) - inflammation , biology , immunology , immune system , ectopic expression , innate immune system , b cell , toll like receptor , acquired immune system , microbiology and biotechnology , cell culture , antibody , genetics
TLR stimulation results in polyclonal B cell activation, ectopic CLIP expression, release of T cell‐derived TNFα, and reversal with high affinity peptide treatment.