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An early circulating factor in severe sepsis modulates apoptosis of monocytes and lymphocytes
Author(s) -
Vaki Ilia,
Kranidioti Hariklia,
Karagianni Vassiliki,
Spyridaki Aikaterini,
Kotsaki Antigone,
Routsi Christina,
GiamarellosBourboulis Evangelos J.
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0410232
Subject(s) - apoptosis , cd14 , biology , sepsis , immunology , flow cytometry , monocyte , caspase , peripheral blood mononuclear cell , programmed cell death , microbiology and biotechnology , biochemistry , in vitro
An early circulating factor exists in severe sepsis/shock modulating apoptosis of CD4‐lymphocytes and of CD14‐monocytes by interaction with the two apoptotic pathways.