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The anti‐tumor agent, 5,6‐dimethylxanthenone‐4‐acetic acid (DMXAA), induces IFN‐β‐mediated antiviral activity in vitro and in vivo
Author(s) -
Shirey Kari Ann,
Nhu Quan M.,
Yim Kevin C.,
Roberts Zachary J.,
Teijaro John R.,
Farber Donna L.,
Blanco Jorge C.,
Vogel Stefanie N.
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0410216
Subject(s) - in vivo , in vitro , biology , influenza a virus , cytotoxicity , viral replication , antiviral drug , pharmacology , virus , virology , drug , biochemistry , microbiology and biotechnology
The experimental anti‐tumor compound, DMXAA, shown previously to be a potent IFN‐β‐inducer in vitro, exhibits antiviral activity in vitro and in vivo.