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IL‐21 and IL‐10 have redundant roles but differential capacities at different stages of plasma cell generation from human germinal center B cells
Author(s) -
Yoon SunOk,
Zhang Xin,
Berner Paul,
Choi Yong Sung
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0409268
Subject(s) - germinal center , cellular differentiation , biology , cd38 , microbiology and biotechnology , b cell , cd40 , immunology , antibody , stem cell , genetics , cytotoxic t cell , gene , cd34 , in vitro
In the germinal center of lymphoid follicles, IL‐10 is more effective in generating terminally differentiated CD138 + PC at the later stage of differentiation than IL‐21.