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Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish
Author(s) -
Loynes Catherine A.,
Martin Jane S.,
Robertson Anne,
Trushell Daniel M. I.,
Ingham Philip W.,
Whyte Moira K. B.,
Renshaw Stephen A.
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0409255
Subject(s) - inflammation , zebrafish , biology , in vivo , neutrophilia , apoptosis , microbiology and biotechnology , tunel assay , immunology , biochemistry , gene
The resolution of neutrophilic inflammation in the zebrafish can be visualized in vivo and manipulated by a range of pharmacological mediators, demonstrating a role for neutrophil apoptosis in this process.