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Enterococcus faecalis translocation in mice with severe burn injury: a pathogenic role of CCL2 and alternatively activated macrophages (M2aMϕ and M2cMϕ)
Author(s) -
Shigematsu Kenji,
Asai Akira,
Kobayashi Makiko,
Herndon David N.,
Suzuki Fujio
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0409235
Subject(s) - enterococcus faecalis , sepsis , ccl2 , biology , cxcl1 , immunology , microbiology and biotechnology , staphylococcus aureus , chemokine , medicine , immune system , bacteria , genetics
Early after burn injury, CCL2 converts resident mesenteric lymph node macrophages to M2a and M2c macrophages that decrease host antibacterial innate immunity against sepsis stemming from Enterococcus faecalis