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RAGE: therapeutic target and biomarker of the inflammatory response—the evidence mounts
Author(s) -
Ramasamy Ravichandran,
Yan Shi Fang,
Schmidt Ann Marie
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0409230
Subject(s) - rage (emotion) , neurodegeneration , inflammation , biomarker , biology , cdc42 , signal transduction , immunology , cancer research , hmgb1 , receptor , glycation , disease , medicine , neuroscience , microbiology and biotechnology , genetics
RAGE may be a biomarker and/or target for therapeutic intervention in chronic disease such as diabetes, inflammation, neurodegeneration, and tumors.