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Lung‐resident memory CD8 T cells (T RM ) are indispensable for optimal cross‐protection against pulmonary virus infection
Author(s) -
Wu Tao,
Hu Yinghong,
Lee YoungTae,
Bouchard Keith R.,
Benechet Alexandre,
Khanna Kamal,
Cauley Linda S.
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0313180
Subject(s) - biology , virus , lung , immunology , cytotoxic t cell , virology , ctl* , immunization , immunity , cd8 , viral replication , influenza a virus , antibody , immune system , medicine , biochemistry , in vitro
Pulmonary immunization is required for generating lungresident memory CD8 T cells, which confine infection within the bronchial tree during heterosubtypic challenge.
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