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Macrophage migration arrest due to a winning balance of Rac2/Sp1 repression over β‐catenin‐induced PLD expression
Author(s) -
Speranza Francis J.,
Mahankali Madhu,
GomezCambronero Julian
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0313174
Subject(s) - inflammation , microbiology and biotechnology , biology , chemotaxis , monocyte , ccl2 , macrophage , stimulation , downregulation and upregulation , ccr2 , chemokine , cancer research , immunology , receptor , endocrinology , biochemistry , chemokine receptor , gene , in vitro
A novel molecular mechanism underlying arrest of monocyte/ macrophage migration important for the physiological maintenance of leukocytes at the site of inflammation.