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Sphingosine‐1‐phosphate can promote mast cell hyper‐reactivity through regulation of contactin‐4 expression
Author(s) -
Olivera Ana,
Kitamura Yoshiaki,
Wright Laurel D.,
Allende Maria L.,
Chen Weiping,
KanekoGoto Tomomi,
Yoshihara Yoshihiro,
Proia Richard L.,
Rivera Juan
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0313163
Subject(s) - biology , mast cell , sphingosine 1 phosphate , microbiology and biotechnology , phosphate , immunology , sphingosine , medicine , receptor , biochemistry
Chronic exposure to sphingosine‐1‐phosphate within, or outside, mast cells causes gene expression alterations that modulate FcɛRI‐mediated mast cell responses, and the onset of allergic reaction.