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Recombinant human mannose‐binding lectin dampens human alveolar macrophage inflammatory responses to influenza A virus in vitro
Author(s) -
Nelson Benjamin,
Zhou Xiuqin,
White Mitchell,
Hartshorn Kevan,
Takahashi Kazue,
Kinane T. Bernard,
Anandaiah Asha,
Koziel Henry
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0313161
Subject(s) - mannan binding lectin , biology , recombinant dna , in vitro , lectin , mannose receptor , collectin , macrophage , immunology , mannose , alveolar macrophage , virology , virus , influenza a virus , inflammation , microbiology and biotechnology , immune system , innate immune system , biochemistry , gene
RhMBL may significantly down modulate human alveolar macrophage inflammatory responses to rhMBL‐opsonized IAV, which may limit lung damage.

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