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Distinct development and functions of resident and recruited liver Kupffer cells/macrophages
Author(s) -
Ikarashi Masami,
Nakashima Hiroyuki,
Kinoshita Manabu,
Sato Atsushi,
Nakashima Masahiro,
Miyazaki Hiromi,
Nishiyama Kiyoshi,
Yamamoto Junji,
Seki Shuhji
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0313144
Subject(s) - cd68 , integrin alpha m , biology , spleen , kupffer cell , macrophage , bone marrow , phagocytosis , cd14 , interleukin 12 , immunology , microbiology and biotechnology , immune system , cytotoxic t cell , immunohistochemistry , in vitro , biochemistry
Kupffer cells consist of resident CD32/CD68+ cells and recruited CD11b+ cells, which engage in bactericidal and antitumor immunity.