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CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model
Author(s) -
Besnard AnneGaëlle,
Struyf Sofie,
Guabiraba Rodrigo,
Fauconnier Louis,
Rouxel Nathalie,
Proost Paul,
Uyttenhove Catherine,
Snick Jacques,
Couillin Isabelle,
Ryffel Bernhard
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0313140
Subject(s) - bleomycin , pulmonary fibrosis , fibrosis , lung , biology , inflammation , cancer research , idiopathic pulmonary fibrosis , immunology , chemokine , pulmonary toxicity , pathology , medicine , chemotherapy , genetics
CXCL6 is expressed in the lung; its blockade reduces lung inflammation and collagen deposition in a mouse model of bleomycin‐induced pulmonary fibrosis.
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