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The Rel/NF‐κB pathway and transcription of immediate early genes in T cell activation are inhibited by microgravity
Author(s) -
Chang Tammy T.,
Walther Isabelle,
Li ChaiFei,
Boonyaratanakornkit Jim,
Galleri Grazia,
Meloni Maria Antonia,
Pippia Proto,
Cogoli Augusto,
HughesFulford Millie
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0312157
Subject(s) - biology , microbiology and biotechnology , transcription factor , gene , nf κb , transcription (linguistics) , nfkb1 , signal transduction , genetics , linguistics , philosophy
Transactivation of immediate early genes, especially targets of the Rel/NFκB pathway, is disrupted in T cells activated in microgravity.