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Length of dsRNA (poly I:C) drives distinct innate immune responses, depending on the cell type
Author(s) -
Mian M. Firoz,
Ahmed Am.,
Rad Mehrnaz,
Babaian Artem,
Bowdish Dawn,
Ashkar Ali A.
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0312125
Subject(s) - innate immune system , biology , myeloid , cytokine , microbiology and biotechnology , cell , immune system , rna silencing , cell type , immunology , rna , biochemistry , rna interference , gene
Using short or long Poly I:C to induce optimal innate immune responses or adjuvant effects depends on the target cell types.