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Evaluation of the Bcl‐2 family antagonist ABT‐737 in collagen‐induced arthritis
Author(s) -
Lawlor Kate E.,
Smith Scott D.,
Nieuwenhuijze Annemarie,
Huang David C. S.,
Wicks Ian P.
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0311174
Subject(s) - apoptosis , arthritis , biology , immunology , cancer research , monocyte , rheumatoid arthritis , biochemistry
Relative resistance to the Bcl‐2 family antagonist ABT‐737 in collagen‐induced arthritis may be explained by Mcl‐1 expression in inflammatory leucocytes.