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TLR7/9 versus TLR3/MDA5 signaling during virus infections and diabetes
Author(s) -
Swiecki Melissa,
McCartney Stephen A.,
Wang Yaming,
Colonna Marco
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0311166
Subject(s) - mda5 , biology , tlr3 , virology , virus , diabetes mellitus , tlr7 , signal transduction , immunology , toll like receptor , innate immune system , microbiology and biotechnology , endocrinology , genetics , rna , rna interference , gene , immune system
Review on the cellular and molecular sources of IFN‐I during virus infections with emphasis on plasmacytoid dendritic cells (pDC) and dsRNA sensors.