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Hypercholesterolemic LDL receptor‐deficient mice mount a neutrophilic response to tuberculosis despite the timely expression of protective immunity
Author(s) -
Martens Gregory W.,
Vallerskog Therese,
Kornfeld Hardy
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0311164
Subject(s) - immunity , apolipoprotein e , immune system , biology , immunology , cholesterol , inflammation , tuberculosis , ldl receptor , cellular immunity , medicine , macrophage , acquired immune system , endocrinology , tumor necrosis factor alpha , lipoprotein , disease , in vitro , pathology , biochemistry
The effects of hypercholesterolemia on host defense and TB immunopathology may depend on the types of elevated lipoprotein particles.