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17(R)‐Resolvin D1 differentially regulates TLR4‐mediated responses of primary human macrophages to purified LPS and live E. coli
Author(s) -
Palmer Christine D.,
Mancuso Christy J.,
Weiss Jerrold P.,
Serhan Charles N.,
Guinan Eva C.,
Levy Ofer
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0311145
Subject(s) - tlr4 , inflammation , internalization , biology , proinflammatory cytokine , escherichia coli , lipopolysaccharide , tumor necrosis factor alpha , endogeny , microbiology and biotechnology , effector , immunology , biochemistry , receptor , gene
Lipoxins and resolvins regulate primary human mϕ responses to E. coli to enhance TNF production and phagocytic killing while reducing TNF production to purified LPS.