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GM‐CSF‐induced, bone‐marrow‐derived dendritic cells can expand natural Tregs and induce adaptive Tregs by different mechanisms
Author(s) -
Bhattacharya Palash,
Gopisetty Anupama,
Ganesh Balaji B.,
Sheng Jian Rong,
Prabhakar Bellur S.
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0310154
Subject(s) - foxp3 , cd11c , biology , immunology , microbiology and biotechnology , cd8 , population , immune system , phenotype , medicine , biochemistry , environmental health , gene
While expansion of natural Tregs requires OX40‐OX40L interaction, adaptive Treg induction requires TGF‐β and TCR signaling.