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FK506 causes cellular and functional defects in human natural killer cells
Author(s) -
Kim TaeJin,
Kim Nayoung,
Kang Hyoung Jin,
Kim EunOk,
Kim Sung Tae,
Ahn Hyo Seop,
Bluestone Jeffrey A.,
Lee KyungMi
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0310148
Subject(s) - biology , natural (archaeology) , microbiology and biotechnology , natural killer cell , immunology , natural killer t cell , immune system , cytotoxicity , genetics , t cell , in vitro , paleontology
FK506‐mediated NK cell defects are associated with impaired IL‐2 receptor signaling and selective down‐regulation of NK receptors.