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Roles for phagocytic cells and complement in controlling relapsing fever infection
Author(s) -
Woodman Michael E.,
Cooley Anne E.,
Avdiushko Rita,
Bowman Amy,
Botto Marina,
Wooten R. Mark,
Rooijen Nico,
Cohen Donald A.,
Stevenson Brian
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0309169
Subject(s) - biology , microbiology and biotechnology , factor h , complement system , relapsing fever , antibody , alternative complement pathway , immune system , immunology , immunity , virology
Macrophages and/or dendritic cells were found to play significant roles in both antibody‐dependent and ‐independent control of B. hermsii infection, while bacterial binding of host factor H was found to be nonessential.