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Macrophage differentiation of myeloid progenitor cells in response to M‐CSF is regulated by the dual‐specificity phosphatase DUSP5
Author(s) -
Grasset MarieFrance,
GobertGosse Stéphanie,
Mouchiroud Guy,
Bourette Roland P.
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0309151
Subject(s) - biology , myeloid , microbiology and biotechnology , progenitor cell , macrophage , macrophage colony stimulating factor , cellular differentiation , signal transduction , immunology , stem cell , in vitro , gene , biochemistry
ERK phosphatase DUSP5 is transiently induced by M‐CSF and its expression increases proliferation and favors granulocytic versus macrophage differentiation in myeloid progenitor cells lines.