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ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer
Author(s) -
Ven Rieneke,
Oerlemans Ruud,
Heijden Joost W.,
Scheffer George L.,
Gruijl Tanja D.,
Jansen Gerrit,
Scheper Rik J.
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0309147
Subject(s) - immune system , biology , effector , immunotherapy , cancer immunotherapy , transporter , autoimmunity , atp binding cassette transporter , cytotoxic t cell , immunology , t cell , inflammation , tumor microenvironment , immunity , genetics , gene , in vitro
Review evaluates the possible physiological roles of MDR‐related ABC transporters on immune effector cells based on reports on their expression patterns and immune‐related substrates.