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DAP12 impacts trafficking and surface stability of killer immunoglobulin‐like receptors on natural killer cells
Author(s) -
Mulrooney Tiernan J.,
Posch Phillip E.,
Hurley Carolyn Katovich
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0213093
Subject(s) - internalization , flow cytometry , biology , microbiology and biotechnology , receptor , signal transducing adaptor protein , immunoprecipitation , transfection , signal transduction , cell , cell culture , antibody , immunology , biochemistry , genetics
Novel interaction between DAP12 and KIR2DS significantly alters surface expression and may impact subsequent cellular functions.
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