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1,4‐Dihydroxy‐2‐naphthoic acid from Propionibacterium freudenreichii reduces inflammation in interleukin‐10‐deficient mice with colitis by suppressing macrophage‐derived proinflammatory cytokines
Author(s) -
Okada Yoshikiyo,
Tsuzuki Yoshikazu,
Narimatsu Kazuyuki,
Sato Hirokazu,
Ueda Toshihide,
Hozumi Hideaki,
Sato Shingo,
Hokari Ryota,
Kurihara Chie,
Komoto Shunsuke,
Watanabe Chikako,
Tomita Kengo,
Kawaguchi Atsushi,
Nagao Shigeaki,
Miura Soichiro
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0212104
Subject(s) - proinflammatory cytokine , biology , inflammation , colitis , cytokine , tumor necrosis factor alpha , immunology , microbiology and biotechnology , pharmacology
DHNA derived from Propionibacterium freudenreichii attenuates colonic inflammation by a direct action on macrophages, leading to decreased production of proinflammatory cytokines.