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Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways
Author(s) -
Vaughn Samuel E.,
Kottyan Leah C.,
Munroe Melissa E.,
Harley John B.
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0212095
Subject(s) - biology , systemic lupus erythematosus , genetic association , signal transduction , disease , pathogenesis , computational biology , genetic predisposition , gene , genome wide association study , immunology , bioinformatics , genetics , genotype , single nucleotide polymorphism , medicine
Review on B cell signaling pathways in lupus risk genes, possibly representing a unique therapeutic opportunity.
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