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Molecular mechanisms of spontaneous and directed mast cell motility
Author(s) -
Lee Jinmin,
Veatch Sarah L.,
Baird Barbara,
Holowka David
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0212091
Subject(s) - microbiology and biotechnology , motility , chemotaxis , biology , orai1 , mast cell , immune system , degranulation , syk , antigen , cell migration , cell , signal transduction , immunology , receptor , biochemistry , stim1 , endoplasmic reticulum , tyrosine kinase
Store operated Ca 2+ entry through the channel protein Orai1 contributes to mast cell spontaneous motility and antigen‐mediated chemotaxis.