IL‐8‐mediated angiogenic responses of endothelial cells to lipid antigen activation of iNKT cells depend on EGFR transactivation | Zendy

Kyriakakis Emmanouil | Zendy; Cavallari Marco | Zendy; Pfaff Dennis | Zendy; Fabbro Doriano | Zendy; Mestan Juergen | Zendy; Philippova Maria | Zendy; De Libero Gennaro | Zendy; Erne Paul | Zendy; Resink Therese J. | Zendy

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IL‐8‐mediated angiogenic responses of endothelial cells to lipid antigen activation of iNKT cells depend on EGFR transactivation

Author(s) -

Kyriakakis Emmanouil,

Cavallari Marco,

Pfaff Dennis,

Fabbro Doriano,

Mestan Juergen,

Philippova Maria,

De Libero Gennaro,

Erne Paul,

Resink Therese J.

Publication year - 2011

Publication title -

journal of leukocyte biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.819

H-Index - 191

eISSN - 1938-3673

pISSN - 0741-5400

DOI - 10.1189/jlb.0211097

Subject(s) - microbiology and biotechnology , angiogenesis , cancer research , neovascularization , biology , mapk/erk pathway , proto oncogene tyrosine protein kinase src , signal transduction , transactivation , chemokine , cell migration , immunology , cell , immune system , biochemistry , gene , transcription factor , genetics

A selective cascade of proangiogenic events occurs following antigen‐stimulation of iNKT cells and attribute EGFR a novel function in inflammation‐driven neovascularization within atherosclerotic plaques.

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