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Defective eosinophil hematopoiesis ex vivo in inbred Rocky Mountain White (IRW) mice
Author(s) -
Dyer Kimberly D.,
GarciaCrespo Katia E.,
Percopo Caroline M.,
Bowen Aaron B.,
Ito Tomonobu,
Peterson Karin E.,
Gilfillan Alasdair M.,
Rosenberg Helene F.
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0211059
Subject(s) - biology , eosinophil , haematopoiesis , ex vivo , immunology , bone marrow , progenitor cell , microbiology and biotechnology , interleukin 5 , cytokine , stem cell , in vivo , interleukin , genetics , asthma
IRW Bone marrow progenitors express fewer IL‐5α receptors and elevated levels of soluble non‐signaling receptor which may contribute to diminished eosinophil differentiation.
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