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Histidine‐rich glycoprotein functions cooperatively with cell surface heparan sulfate on phagocytes to promote necrotic cell uptake
Author(s) -
Poon Ivan K. H.,
Parish Christopher R.,
Hulett Mark D.
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0210087
Subject(s) - biology , glycoprotein , microbiology and biotechnology , heparan sulfate , histidine , cell , biochemistry , membrane glycoproteins , amino acid
HRG enhances the phagocytosis of necrotic cells via a heparan sulfate‐dependent pathway that is inhibitable by heparin.