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Oxidative stress can alter the antigenicity of immunodominant peptides
Author(s) -
Weiskopf Daniela,
Schwanninger Angelika,
Weinberger Birgit,
Almanzar Giovanni,
Parson Walther,
Buus Soren,
Lindner Herbert,
GrubeckLoebenstein Beatrix
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0209065
Subject(s) - antigenicity , biology , oxidative stress , peptide , oxidative phosphorylation , virology , antigen , immunology , microbiology and biotechnology , biochemistry
Oxidative modification of the CMVpp65 495–503 peptide influences binding to the T‐cell receptor and results in lower proliferation and IFNγ production of CMV‐specific CD8 + T cells.
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