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Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL‐37 is not proinflammatory to phagocytosing macrophages
Author(s) -
Li HsinNi,
Barlow Peter G.,
Bylund Johan,
Mackellar Annie,
Björstad Åse,
Conlon James,
Hiemstra Pieter S.,
Haslett Chris,
Gray Mohini,
Simpson A. John,
Rossi Adriano G.,
Davidson Donald J.
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0209050
Subject(s) - cathelicidin , proinflammatory cytokine , biology , phagocytosis , apoptosis , immunology , necrosis , macrophage , phagocyte , microbiology and biotechnology , tumor necrosis factor alpha , innate immune system , inflammation , immune system , in vitro , biochemistry , genetics
LL37‐induced secondary necrosis of apoptotic neutrophils with release of granule contents potentiates the anti‐inflammatory activity of apoptotic neutrophils on macrophages.