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The functional significance behind expressing two IL–8 receptor types on PMN
Author(s) -
Stillie RoseMarie,
Farooq Shukkur Muhammed,
Gordon John R.,
Stadnyk Andrew W.
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0208125
Subject(s) - cxc chemokine receptors , chemotaxis , biology , receptor , chemokine , chemokine receptor , microbiology and biotechnology , innate immune system , immunology , signal transduction , biochemistry
The presence of two CXCL8 receptor types combined with the inflammatory roles of PMN has led to interest in whether each receptor type contributes to unique functions.