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FMNL1 promotes proliferation and migration of leukemia cells
Author(s) -
Favaro Patricia,
Traina Fabiola,
MachadoNeto João Agostinho,
Lazarini Mariana,
Lopes Matheus Rodrigues,
Pereira João Kleber Novais,
Costa Fernando Ferreira,
Infante Elvira,
Ridley Anne J.,
Saad Sara Teresinha Olalla
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0113057
Subject(s) - k562 cells , rac1 , biology , haematopoiesis , leukemia , cell growth , microbiology and biotechnology , cell culture , gene silencing , cell , stem cell , immunology , biochemistry , gene , genetics , signal transduction
FMNL1 regulates leukemic cell proliferation, clonogenicity, migration, and interaction with endothelial cells, supporting a potential role in leukemogenesis.